CONSIDERATIONS TO KNOW ABOUT AHU'S

Roughly eighty% of TTP is induced by deficient action of ADAMTS13. ADAMTS13 deficiency can be constitutive, on account of biallelic ADAMTS13 pathogenic variants; or acquired, as a result of an inhibitory antibody. Evaluation of ADAMTS13 action is executed using tests dependant on the capability of the protease to cleave regular VWF multimers in vit